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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '498a92d8a3b571d169b2959d8e68cb7ea39ee2e32caa72bf9b925ff0e09cf238' 
  AND token = 's7+sLSIrH23v2GeOriZyVgl7AJxY9DGZf9Y7Fv9V2Hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}