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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27492b3af3e8f345b36e60db9608cf5f78ef25bd47d82e00f4f46c2edc8bcf36' 
  AND token = 'aKL/vPM8CRz8cFDd6751mOOc18Z77LFKCdtK4jbIVuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}