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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b44a4f907fc587f9a2992539614f0e53518b2caf04af2fb5463f1ad47b794d' 
  AND token = 'JSF/TtYxq2jGPXzl3cHsaQmVSZExOREsQKQtaKT5HfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}