SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c40839ecfc13aca1e2d82b73ca11744e6fad4ed1ebd6959ea1a3fb2c895a001' 
  AND token = 'oFyNZwryXE76x/vA2K2GLmaXSPBgD9acFxRyFKgiaWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}