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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08caa41722aae31d33b8d6f285fc9e22d700292667d988a002cd1b223f8a060c' 
  AND token = 'eieiEMJ+o6UICp5srArsIlYKxSEdx1vkg6+1aY4y+nQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}