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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7490a335427f6d727259926db652c86c6f35488a261dc141e5b910625dafcdd6' 
  AND token = 'NPiZMoscxHRMP3m6gVe8fLPQvoYF9Z6END/Bncw/u/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}