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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f655eb21ece9c951a0617dd2a55a06ebede24bb0694e45e38625b017d9e386a4' 
  AND token = 'caU//bZR5V1rcA+T9FFLO6mdrRJLgz+nphw1pZxDrf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}