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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b3605a5fc04fb6240d363af63f40e673e302261a174a78c8569c479ebf92a12' 
  AND token = 'psMf1Ku4pfM1BDhBNObK0e5ltW2aMRrKvs+/B0nW7vI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}