SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd582c6ef14c98dd5c3aa97cdb296857cdb1da3fde893d577cd6b35f51eaded36' 
  AND token = 'YNs/5Ug3bqY90TmRWuyWBEpP2KUWpEfoFo4CkbqcFsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}