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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c2480d2dd222ba0580158d572172c447d99e4a6a13d08c931dc0c424fcc3aba' 
  AND token = 'lxY0HK6jLU5FuxQs49zssdsmCF9o46j0Ol86wWHOWd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}