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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58a227722da42e3dc6cd33d76b40edfb2f09cfce3306f400161e45cc4d4e6313' 
  AND token = 'CTwAT+jJzeafs4LjofO+bSs1IaSSI54JAE6wB6zFUIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}