SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddc75b514e8159be5ad230b2f36bd1aaa91b062d3dbe4772b0d02add5bda4d43' 
  AND token = 'azZ+G8vPtcB9FanfQJ/yDQeAZ3X+8NjPnO/daZgOJVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}