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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83433d37c05eef6e5229bf5d720d2163ae34cef0cbde77d8522719e64886d6b7' 
  AND token = '3TmvVuKivmhSulycclMymd2EQn+ER2qlQzBlEKxEBws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}