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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2637b040a23ade181ca26998ef6c2045440bfa9e4d3babaec4eab82227ad279' 
  AND token = 'nxB2JNVGgimrIp8fleoevCZxqWufEwZI5z8u+T0TJCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}