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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8872ecde6259cf2c43d38f7472d30c90fef2b512b0e7f4726ffe17b44ed79654' 
  AND token = 'UKQIommmWLX2++6Tzhh6FTRcqZQA8w+rIF6iIWEx10k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}