SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2e351c45c86de459a365d2a515e12e09bf394fd857cad53fc8812f87e3dc6e3' 
  AND token = 'zKm/a60mxhKma6rFh7znb7qzlkhPPnYQwI6jIqVPKK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}