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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '901d1aaf0ff56b64bd9fa871e569fb3b88356b4f9b2c7c072b112369472d8d10' 
  AND token = 'kM0Su0O0TwMvlbOYL16rzfQvftr5WaVs8ep+ZBXNUXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}