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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1446840deea30e5ebbca6064fd308fcc173f35af232b737bb7301a091c1a356' 
  AND token = 'JnUykpCQpOJ4AC5/2/QXe3pOCrIokKFLXrP4uqm1rsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}