SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e02c1a725fdf840248f6f2cbb227cd41b0a5aab526a472b5adaf6b8fc37b831c' 
  AND token = 'nxrOJ9WwX+l6QwEHh18e0gErvV+7LWiFHhcVhIROpkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}