SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '391d32c437b6ebaa888db50d10d4bbd69be93ff807a8926df0221d90161f7b6b' 
  AND token = 'SIvHRnuTK7VLBBYBZ2Tjqxi8uNW9NsYjkvHK26AVQqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}