SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '604be937077bc3318b70831929f8cef483994b5196b4ae081290225de1ebc3cd' 
  AND token = 'vILyEC1DBBqRIoYkkV4y0Dgp7I20yoBd9aDWHwUw2Pw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}