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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dbd0d1302980b527eb7e5f229cb5bc849c31f8fc58476071e1e14ec48079ef1' 
  AND token = 'Z1Um6Lh5lOwRc/IQ20jkaN+zBEwcfOSSZksY9ipv2Yk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}