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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67249c71c06aebb0cac403f2be4cad2f002c6fd3d1f883b010874b5488d63f58' 
  AND token = 'WZ1Fauy/ZPHC1tOzsVsHQTnmAmShLjb1WZpE8aZiPjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}