SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe0f6e736185306a91a62a5b5f44aab1825c43d7d85e0cd5459b95b5d546161c' 
  AND token = 'WUt+ZqA69tmnQc2Y/FFe15pvmgo6TXqVLFjMm6iAsPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}