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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e48640e793087c3d15ee2403690541f3b9bfc414c30de99f2c32e470cc54fd' 
  AND token = 'ZW8Yt2D0qdod8RGR4wa/we7XtaPcXW8Lnxq19kgimrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}