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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '680a0cb22a176b392d2c5953b204f8abe8b15bb81bdf9428b5413ce593c3206b' 
  AND token = 'BywBp2fIqItXtR52P5a7h+qReUhug3RM79JqVdBh6TA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}