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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7a6ab131a19a73e7de23d247d551428af117f1c655eeafd71b380feb2b9b978' 
  AND token = 'm90m1P3rU0EnQDnMkxKADrH3PD28aVm5jGC4MDg8UQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}