SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5edef3cd6b205eb91ce6adca220b8bfb265f5e50c19224dca6ba78bffab1a69' 
  AND token = 'YFHYbcwuPXxAR0uTfFgkafC+gY7pjNTUuj5a55h4bFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}