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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c8ea9284e49098553712529e5f57f61bfdaae275b3271d8d4622fc242c01d42' 
  AND token = 'KANVqC8agPsKo2VQGa4qdADODpeIs7AXpBthfyL7Sdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}