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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10ca2a13b072c8f4a5a013630fb820531aaff85e4beff265d32adc2d8978df2c' 
  AND token = '0/0bVv+xDq9ilkdjLwomtTOFXuxf4Pum86OOVlDBbeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}