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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9044d9593ae9ebc255dd7eda2936b9e525b997ad612e180b9e8da0e736de838' 
  AND token = 'RZfp8+xL35VMsyjo25aOTeJk6UqW2uZoiWIk4Br4U6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}