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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6635fcc578bdc79b617a39778f5a15a52825a8d1359594457e18ea03ba6ab285' 
  AND token = 'BnFsQn07v/ViAH3G1WKYByvd0f0XKRG0ngXaxos1nrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}