SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5a1f512d2304f0ba1114d60b22942d68dc7a44c769c818fa190f40e284467f4' 
  AND token = '0RSybZr2UUKnNY3RgUsZ2XzNtakN7tlamPwCxBFZF30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}