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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3825988735a062065d7ed2cdaabd5102431e9070208cc9de65cc38325a8edd49' 
  AND token = '0uoW4vpk0nBI2lClecDNv4k7LIvP2c58iLcZkjj2zrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}