SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63dd88372455536cb24ca0ebf7dec6ae4985d099b60b821223ee072352d03195' 
  AND token = 'vqwvkT3dbNYPwGT0MdMd4DmSpX3IStodxOeORPf3QR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}