SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e25b31b7189e7fa8be550aead7898925bd1d5382a92265bafc78b6192d781415' 
  AND token = '8wxpx8oZYp+O4nvvpi3yp/rjdfdjxPR8VKFaplzmZQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}