SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb6f8d78f2bd423892e0022cd445d7b311d65caa91448159996028a2ecbe0e7a' 
  AND token = 'CdcS8WWEAHVu8mcfN9WLETCrO7CmU8j8db63Pv4iWYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}