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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b1721920499912ca9f18df5f168f60b6ae7778f668d6d4d88c1f460217ef1e3' 
  AND token = 'DPOvMJAkmlX9s0ddgBI38GeFx+f14lEf2XBALj81kH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}