SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e754ea58e73e1f39c5a72308786a00550802a4dc63ddd02b2ef716d7d731ba4' 
  AND token = 'tYVwy1rOfiE4Pasor54U8fP1mQCkP92ck4+d7Hsk29M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}