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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14277bb57766a5697b520f0c5adc9b104401c0fc0227df4590699bb6b2e6cff1' 
  AND token = 'XyU1YSoyHZ0hFkGwLNb6rKRl7vZWePn+O2sh9tBtbzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}