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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d98bbdd3d86169a8afc57270ae40d3566cfc3a3db3cd361466e6277a102f3e5' 
  AND token = 'nnjWnBPjxf3yS4mLxQx0CA3tzv+WsHSyNPFZAR3ZmHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}