SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c7adcebdc6f7ee3c0173c586ec0eacfde17c6c4ccbf2f65f3e3d9812089a486' 
  AND token = 'lGmatQ84Q8bx030IaF+fqP4kmenwkpKsDwjhOEMdhM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}