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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6e12cafe652d421a171f2a49a86a23c3aeb9a5e69b0c9fa276390be3cb3c30a' 
  AND token = 'UFwe6qLAqs6NKG7dkxYuNxUG5hamngvFlkrupfEDDK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}