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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b49b6800170144f456fbe4ee3ccdf3ac05e5de3a1f004d268d15dc6d891a11b' 
  AND token = 'Vs8nsw7MgduOS0j03IR3QSVO+wjYPZUfrHJ7WxpTDZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}