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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d4e46078d5c1eedb532c737c64bcd20b5ec6b9cac06b196286ccacb0b8a17f0' 
  AND token = 'CEtIyCwNs4Dtl6zuzhtaq38mhi7Py+27JlK1dUo7yqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}