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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd718e1c4d980ec86564ca4a302cd1b9308e64348cff4a50208984462781ad844' 
  AND token = 'l8FN2jfRRO8gytsjUgic1NKoB+jmrEZdo68lK/TuyQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}