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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27e20cb2936f76bed4582a8c1c6a1f9114cc3d765b1b2dd4971bfbac5925a525' 
  AND token = 'acZOI54bISw/T9y25G0sfeDXAohRF4zE1tyqqcS3dKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}