SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61261c19cca71e5e866283980b2dc4c3ec0aad7c046967d541b192de23a8c352' 
  AND token = 'XUf32dKcdEj8f2DV1RURPGBoqvGXhqcFBggFC4O3dKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}