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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d3589ac94c2a457b14ada83f8c9a7a72cceb92cfb6fd05b7ebbe279197289e4' 
  AND token = 'S97mdS1o8nJkaS635oIF8bRvZVgubIT9twXCjqN9/8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}