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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01f3606d223b15312b755b25cab3c0e6272efc71257e0becbb725da8b97c2b52' 
  AND token = 'VlHu/gZ+TvnUItcy8G6b6wZyEVB3TQbKmUiBf1WUPy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}